Cocaine Addiction Mechanism
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Altered Perception Of Reward In Human Cocaine Addiction
Altered Perception of Reward in Human Cocaine Addiction Brain-mapping, psychological studies support mechanism for compromised control in drug addiction October 15, 2006 ATLANTA, GA — People addicted to cocaine have an impaired ability to perceive … View Full Source
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National Institute On Drug Abuse RESEARCH
Underlying Cocaine Addiction 145 U.S. Department of Health and Human Services • Public Health Service • National Institutes of Health logical mechanism for cocaine reinforcement provides a rich substrate for … View Doc
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Aripiprazole And Ropinirole Treatment For Cocaine Dependence …
D 1, D 2 and D 3 receptors seem to be implicated in the mechanism: sub-chronic cocaine administration seems to straighten the effect of D 2 agonists on sexual Novel approaches to the treatment of cocaine addiction. CNS Drugs 2005; 19: 13-15. [11] … Get Doc
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The Official Journal Of The American Academy Of Addiction …
This type of mGluR agonist in cocaine addiction. One compound that indirectly stimulates presynaptic mGluRs, N-acetylcysteine, has been investigated both preclinically and in a small clinical trial (mechanism #2 in Figure … Fetch Here
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Cocaine Cue Sand Dopamine In Dorsal Striatum:Mechanism Of …
Brief Communicati ons Cocaine Cue sand Dopamine in Dorsal Striatum:Mechanism of Craving in Cocai ne Addiction NoraD.Volkow, 1 Gene-Jack Wang, 2 Frank Telang, 1 JoannaS.Fowler, 3 Jean Logan, 3 Anna-Rose Childress, 4 Millard Jayne, 1 Yeming Ma, 1 and Christopher Wong 3 1 National Institute on … Retrieve Here
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Dual Dopamine–5-HT Releasers: Potential Treatment Agents …
Potential treatment agents for cocaine addiction Richard B. Rothman1, Bruce E. Blough2 and Michael H. Baumann1 two categories based on their molecular mechanism of action: uptake inhibitors and substrates (Box 1). Cocaine … Fetch Here
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Molecular Mechanism For A Gateway Drug
ADDICTION Molecular Mechanism for a Gateway Drug: Epigenetic Changes Initiated by Nicotine Prime Gene Expression by Cocaine Amir Levine,1,2* YanYou Huang,1,2 Bettina Drisaldi,1 Edmund A. Griffin Jr.,2,3 … Access Document
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Neuroadaptive mechanisms Of addiction: Studies On The …
Keywords: Addiction; Amygdala; Corticotropin-releasing factor; Allostasis; Reward; Ethanol; Cocaine 1. Animal models of addiction Drug addiction, also states of drug abstinence providesa powerful motivational force for the compulsive drug taking that characterizes addiction. One likely mechanism for … Access Document
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Meriem Gaval-Cruz And David Weinshenker
Disulfiram and Cocaine Addiction Cocaine and Alcohol Co-abuse According to clinical and epidemiological studies, fifty to ninety percent of Human Laboratory and Animal Studies To understand how disulfiram treatment affects an individual's response to cocaine, and to shed light on the mechanism driving the … Fetch Doc
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Groundbreaking RFUMS Research Into cocaine addiction …
Groundbreaking RFUMS research into cocaine addiction published in foremost Nature science journal mechanism that helps to explain why craving for cocaine increases rather than decreases … Retrieve Content
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CocaineCuesandDopamineinDorsalStriatum:Mechanism …
CocaineCuesandDopamineinDorsalStriatum:Mechanism ofCravinginCocaineAddiction and in cocaine addiction in humans. It also suggests that com pounds that could inhibit cue-induced striatal DA increases … Fetch Content
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Cracking The Metabolism Cocaine
Department of Chemistry and Biochemistry University of Guelph Overview general description of Cocaine Brain mechanism Depression Over dose: respiratory arrest Myocardial infarction Arrhythmia Seizures Cocaine Dependency : Three classical clinical characteristics that define addiction … View This Document
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N-Acetylcysteine May Reduce Cocaine Craving
The cocaine-dependent, according to findings published in the July issue of the American Journal of Psychiatry. "We may have a completely new pharmacological mechanism for treating cocaine addiction and perhaps other … Get Content Here
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CHAPTER 7 PSYCHOMOTOR STIMULANTS
Neurotransmitter Actions of Cocaine Cocaine: Physiological Effects of Short-term Low-Dose Cocaine Use Cocaine: Psychological Effects of Short-term Low-dose Cocaine Use Cocaine: Effects of Long-term High Dose Cocaine Use Cocaine: Treatment of Cocaine Addiction Amphetamines: Mechanism of … Access Content
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The Abuse Liability And Therapeutic Potential Of Drugs …
Fourteen drugs with a primary mechanism of action at either the DA, 5-HT or NE systems were identified that had been tested as potential treatments for cocaine addiction and had also been evaluated in either the self-administration or conditioned place preference paradigms in animals. … Read Content
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Molecular Mechanisms Of Drug Addiction
Opiate, and possibly cocaine, addiction in a number of drug- responsive brain regions. The mechanism of acute opiate action in the LC, based on electrophysiological and biochemical studies, is well established … Retrieve Here
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Enhanced Choice For Viewing Cocaine Pictures In Cocaine Addiction
Key Words: Choice behavior, cocaine addiction, craving, IAPS pic-turesreward,neuropsychology,salience,unconsciousmotivation C ocaine–addicted individuals pursue cocaine and cocaine-related stimuli over nondrug-related goals (1). The under-lying mechanism may involve reduced striatal dopamine … Retrieve Content
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SYNAPTIC PLASTICITY IN COCAINE ADDICTION Margarida Corominas …
In physiological conditions, the ability to reverse LTP at striatal synapses functions as a mechanism for "forgetting" maladaptive habits, thus the lack of ability to reverse LTP may have important consequences in drug addiction. Increased BDNF levels in VTA neurons during withdrawal from cocaine plays … View This Document