Cocaine Treatment Dat
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Psychostimulants And Monoamine Transporters: Upsetting The …
Amphetamines and cocaine, as well as therapeutic drugs for the treatment of depression, addiction and attention de?cit of cocaine binding to DAT is distinct from that of sub-strates, and that cocaine induces a differential conforma- … Access Doc
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Pharmacophore-BasedDiscoveryofSubstitutedPyridinesas …
Properties of cocaine.2 As such, considerable emphasis hasbeendirectedtowardDATasamoleculartargetfor developing a pharmacotherapy for the treatment of cocaine addiction and abuse.1 4 Novel DAT inhibitors … Access Full Source
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Serotonin And The Therapeutic Effects Of Ritalin
Given in the treatment of ADHD (30 mg/kg intraperitoneally in the mice versus 0.1 to 1 mg/kg orally in human patients). The tempo ral course of methylphenidate’s calming ef fects in the DAT-KO mice was very different from those of cocaine, amphetamine, or the … Access Doc
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Neurobiology Of Cocaine Addiction
The acute reinforcing actions of cocaine. Inactivation of both the serotonin SERT and dopamine DAT transporters in the brains of mice dramatically therapies in the treatment of cocaine addiction. Potential use of Buprenorphine for cocaine … Document Retrieval
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Faster Onset And Dopamine Transporter Selectivity Predict …
DAT inhibitors as medications for cocaine abuse is their potential for abuse. Preclinical evaluationof pharmacotherapies for treatment of cocaine and opioid abuse using drug self-administration procedures. … Access Full Source
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Adult Drug treatment Plan 2006/07 Part 3: Planning Grids
Conduct a review of cocaine and alcohol provision with a view to providing a structured pathway for clients aged 26 and over presenting with Ongoing DAT / Treatment Services ACORN move on accommodation funded via DoH capital grant will be fully utilised to provide stable housing for Recovering … Fetch Full Source
Quantitative Pharmacologic MRI: Mapping The Cerebral Blood …
A number of important classes of medications used in the treatment of psychiatric disorders and many drugs of abuse target plasma knockout of DAT has a small but signifi cant effect on the immediate response to cocaine in brain regions thought to be involved in cocaine reward, knockout of DAT … Retrieve Doc
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New Clinical Information For Treatment Of Cocaine And Meth …
New Clinical Information Regarding the Treatment of Individuals for Cocaine and Methamphetamine Dependence initial resolution) 11 single flashback 9 Recurrent flashbacks Yui et al., 2001 Polymorphism in DAT … Return Document
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Evaluation Of The Blood-Brain Barrier Transport, Population …
Dates for the treatment of cocaine abuse. Cocaine exerts its psychomotor stimulant and reinforcing effectsprimarilythroughtheblockadeofthedopaminetrans porter (DAT) (Ritz et al., 1987; Carroll et al., 1992; Self and … View This Document
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The Abuse Liability And Therapeutic Potential Of Drugs …
IV.B.4.c. Methylphenidate Methylphenidate (Ritalin) is currently, and most frequently prescribed for the treatment of attention deficit and hyperactivity disorder (ADHD). Neurochemically, methylphenidate is similar to cocaine; its affinity at DAT and onset of action are nearly identical to cocaine, but … Access Content
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[11C]ALTROPANE, A HIGHLY SELECTIVE LIGAND FOR THE DOPAMINE …
Claudio Naranjo on Movement During Ibogaine Therapy “A comfortable couch or bed must be considered part of the setting for the treatment, for is positioned to integrate food reward with coordination of movement Cog-Emotion Role of the Cerebellar Vermis In Cue-Induced Cocaine Craving DAT … Visit Document
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Guest Editors – Rao Rapaka And Wolfgang Sadée Role Of …
VMAT-2 function are caused by psychostimulant treatment, and that unique effect pro ? les exist for different drug types in blockade of DAT by cocaine leads to a rapid increase in DA uptake in synaptosomes prepared from treated rats, 12 a … Retrieve Full Source
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A Novel Strategy For The Treatment Of Cocaine Addiction
A Novel Strategy for the Treatment of Cocaine Addiction STEPHENL. DEWEY, 1,6, * ALEXANDERE. One strategy is to directly target the DAT with a high-affinity cocaine analog, thereby blocking cocaine's action (Morgan, et al., 1997). … View Document
Presynapticregulationofdopaminergic Neurotransmission
With chronic cocaine treatment, most evidence points to a decrease in DAT expressionfollowingasuf?cientwithdrawalperiod(Kuhar andPilotte1996),althoughbothdecreasedandincreased … Doc Viewer
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Business Opportunity Neuropeptide Y Y5 Antagonist For The …
Target for cocaine addiction treatment is performed by including NPY Y5 knockout mice in the Dopamine-containing neurons (DAT-positive) in the VTA contain Y5 receptors. … Fetch Here